Endocrine Abstracts

Background and aim: Carotid intima-media thickness (IMT), as assessed by B-mode ultrasound, is a commonly used clinical marker that reflects systemic burden of atherosclerosis and value of IMT at or above 1 mm at any age is associated with a significantly increased risk of myocardial infarction. On the basis of such findings, we aimed to clarify the relationship between carotid intima-media thickness and anthropometric and metabolic parameters in virtually healthy subjects.</p...

Background and aim: It was known that NT-proBNP levels increased in cardiac failure. But, NT-proBNP levels in different thyroid status still unclear. We aimed to evaluate serum NT-proBNP levels in both of hyperthyroid and hypothyroid patients without cardiac insufficiency.Subjects and methods: Thirty nine patients with hyperthyroidism (43.0±16.5 yr), 25 patients with hypothyroidism (35.4±13.9 yr) and 34 ages matched euthyroid subjects (41.4&#17...

Background and aim: Somatostatin analogues such as octreotide acetate were used in acromegalic patients as primary or secondary treatment. In this study we aimed to report completely disappearing of adenoma and clinical cure in 3 acromegalic cases that rejected surgical treatment.Case1: E.A (62 years old, female) She reported enlargement of his hands, deepening of his voice and increases in shoe size. MRI revealed a macro adenoma which was spread to cave...

Background and aim: Hyperprolactinemia may associate with insulin resistance. This fact has been determined by many studies with methods which show insulin sensitivity. In this study we aimed to search insulin resistance with golden standard euglycemic hyperinsulinemic clamp technique on hyperprolactinemic patients.Subjects and methods: This study was performed in Endocrinology Department of Dicle University. Sixteen patients with microprolactinoma (mean...

Aim and objective: Mucormycosis is a rare life-threatening fungal infection. Immunocompromised patients are often affected. We report a rare diabetic patient with pancreatic adenocarcinoma who was presented diabetic ketoacidosis and rhino-orbito-cerebral mucormycosis.Case presentation: A 66 years old man with pancreatic adenocarcinoma and type 2 diabetes mellitus was presented diabetic ketoacidosis and severe infection of the facial sinuses, orbita, and ...

Aim and objective: Mucormycosis is a rare life-threatening fungal infection. Immunocompromised patients are often affected. We report a rare diabetic patient with pancreatic adenocarcinoma who was presented diabetic ketoacidosis and rhino-orbito-cerebral mucormycosis.Case presentation: A 66 years old man with pancreatic adenocarcinoma and type 2 diabetes mellitus was presented diabetic ketoacidosis and severe infection of the facial sinuses, orbita, and ...

Objective: Treatment of diabetic foot ulcer is complex and difficult. Blood glucose regulation, debridment and surgical revascularization are used in management of diabetic foot ulcer. Intralesional Epidermal Growth Factor (EGF) is a new treatment approach for diabetic foot ulcer. We report our experience with eight patients with diabetic foot ulcer who were treated by intralesional EGF.Patients and methods: A total of eight patients whose diabetic foot ...

Objective: Diet, lifestyle changes, medical agents and surgical approaches are treatment options in obese patients. We reported two morbid obese patients who lost 25 and 21% of their previous weight respectively with only lifestyle changes and orlistat therapy.Case 1: Forty nine year-old woman had type 2 diabetes mellitus for 20 years. She took premix insulin twice a day. Her height was 157 cm, her weight was 120 kg, body mass index was 48.6 kg/m2</...

Introduction and aim: Overt thyroid dysfunction is well recognized to affect weight, but the influence of minor perturbations of thyroid function remains unclear. There is ongoing debate regarding the influence of minor changes in thyroid hormones status within the normal range and BMI. The aim of this study was to investigate the association between thyroid function within normal ranges and obesity via BMI and body compositions analyzed by bioelectrical impedance.<p class...

Aim and objective: The aims of this study were to determine the incidence of breast cancer molecular subgroups, to investigate the relationship between autoimmune thyroid disease and prognostic and predictive factors in patients who were diagnosed with breast cancer.Materials and methods: One hundred one patients who were followed up with the diagnosis of breast cancer at our Endocrinology and Medical Oncology Departments were included. Patients are divi...